Improving PROTAC properties via single-point changes to linkers
We explore how computational methods can be applied to proteolysis targeting chimera (PROTAC) design, to effectively tackle some of the ...
News
The better your library is designed, the better your chances of a successful screening hit. Given knowledge of the protein target, a focused approach to library design leads to far higher hit rates than high-throughput or random screening.
Discover how templates built by Forge can be used to screen compound collections, or fragment libraries, to help to build focused screening libraries with a high chance of success. Read our article in Genetic Engineering News (15th September 2012, Vol. 32, No. 16).