Improving PROTAC properties via single-point changes to linkers
We explore how computational methods can be applied to proteolysis targeting chimera (PROTAC) design, to effectively tackle some of the ...
News
An updated version of the Spark™ reagent databases, based on the eMolecules Building Blocks collection, is available.
It’s very easy to update the Spark databases to ensure you are accessing the most up to date reagent availability information; follow these steps:
When a database is selected, you will be prompted that: One or more of the selected databases has a newer version available. [Update]
.
[Update]
hyperlink will launch the Spark Database Updater where you can choose to update only the database you are using for your search (click on the Update
highlighted by the orange rectangle in the image below), or all databases for which there is an update available (click on the Install
or Update Displayed Databases
button highlighted by the blue rectangle in the image below).Further details are provided in the updating Spark databases webclip or on the installing Spark reagent databases page of our website. You can also read more about the data content of Spark databases.
If you’re not yet a Spark customer, request an evaluation to learn how to generate highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.