Discovery
Premier computational chemistry CRO
A unique perspective to advance your discovery project performance
We have extensive industry experience and a proven track record in delivering drug discovery projects
For your next project our molecular modeling experts, and CADD scientists, can work alongside you from the ground up, giving expert advice and guidance about how to accelerate your assets through the pipeline
- Discover fresh ideas
- Remove roadblocks
- Add direction and insight
- Reach your next milestone faster and more cost effectively
- Understand as much as possible about the systems your scientists are working on
- Direct your resources in the direction most likely to succeed, saving you time and money
Optimize the value of your research investment to spark new methods and ideas for your project by collaborating with our experts, who have extensive industry experience.
Testimonials from Cresset Discovery customers
Working closely with the Cresset Discovery team we aimed to identify a putative binding pose for a lead series in published PDB coordinates that was not only consistent with the kinetically deduced MOA but explained the established SAR as well. The furnished results were able to satisfy these goals and then be applied prophetically for ligand design purposes.
Twentyeight-Seven Therapeutics, USA
We sought the scientific expertise within the Cresset Discovery team to utilize their novel field and shape-based virtual screening methods in Blaze™, and their proprietary Electrostatic Complementarity™ technique to help identify a backup series for our target effectively and efficiently. Ultimately we identified 9 novel chemotypes that were clearly distinct to those arising from docking and pharmacophore virtual screening approaches, which was an exciting outcome for us.
Dr Zara Sands, Head of CADD and Informatics, Confo Therapeutics, Belgium
Through the work presented to us I was particularly impressed with the data management and visualization within Forge, so the next step was for us to use it in-house. We will use Forge alongside our continuing consulting work with Cresset to aid in the development of our understanding of the SAR and design of future antifungal agents.
Dr Graham Sibley, Head of Chemistry, F2G, UK
We really like the powerful combination of excellent software tools and molecular design expertise which we get from working with Cresset.
Dr Graham Sibley, Head of Chemistry, F2G, UK
Cresset is a valuable partner in our drug discovery programs. Their deep knowledge of computational chemistry and its application to drug discovery is enabling us to progress multiple projects across a wide range of target classes very quickly and cost-effectively. Cresset has consistently delivered insightful support to our drug discovery efforts. In our experience, their knowledge, responsiveness and collaborative approach have set them apart from their competitors.
CEO, Pharmaceutical company, UK
Cresset Discovery’s computational experience and high standard of scientific support is ideally suited to help drive the next stage of this project.
Dr Richard Boyce, Senior Director of Research at PhoreMost