Forge™ is a powerful computational chemistry suite for understanding structure activity relationship (SAR) and design. It gives you control and insight into your activity data enabling you to plan the direction of your project with confidence.
Forge uses Cresset’s patented ligand comparison method to align and score molecules using their electrostatic and shape properties. It builds qualitative and quantitative 3D models of activity, helping you to understand how compounds interact with protein targets.
Use Forge to:
You can also ask Cresset Discovery Services consultants to run a proof of concept using Forge.
Forge is available on Windows®, macOS® and Linux®. It can be accessed as an intuitive graphical user interface and as a series of task-focused command line binaries. Forge capabilities can be accessed through KNIME™ nodes and Pipeline Pilot™ components.
Machine Learning methods