Support resources

Introducing the Conformation Explorer in Forge 10.5

Field-based virtual screening: Blaze demo server

Ligand design in the protein active site

Navigating complex SAR with Activity Atlas

Tagging by cluster using Activity Miner

Learn how to tag compounds in a Forge project by cluster membership, following a cluster analysis run within Activity Miner

Interacting with structures in Flare

Learn how to interact with proteins, protein chains, water molecules and small molecule ligands in the Flare GUI

Ligand growing with Spark

How to grow a starter molecule into a new space, guided by existing ligands, mapping a different regions of the same active site

Macrocyclization using Spark

How to use Spark to macrocyclize a molecule

Flare Viewer

Free licensing option for Flare, fresh insights for structure-based design

Forge V10.6 release features

Rapid and simple Blaze database population and searching using KNIME and Forge

In this case study, a Blaze™ database of approximately 200,000 compounds from ChEMBL2 was prepared in a seamless manner using a KNIME workflow and standard Blaze database creation routines.