FieldTemplater v3.0 Released

The release of FieldTemplater v3.0 completes our two year project to introduce parallelized operation to our desktop applications.   All our applications will now use all the computing resources available on modern desktop machines, giving significant speed increases for all users. FieldTemplater is not limited to just your local machine; using remote “FieldEngines” you can further increase the speed of calculation. Simply specify the location of the remote resource – your neighbors Windows box or Amazon cloud or a local compute cluster- and FieldTemplater will connect to and use these resources to give a massive speed bonus to your calculation.

In addition to a completely new architecture, FieldTemplater V3.0 comes with numerous improvements to the user interface to enhance your experience.   Just like all our other applications, we provide a simple wizard to guide you through the process of setting up and starting your experiment, however, the individual steps have been cleaned up giving fewer mouse clicks and simpler operation. Should you step away from the wizard, you will find we have greatly improved the interaction with other applications through the introduction of extensive copy and paste operations.  You will now have significant control over the conformation space used in calculations by simply copying the conformations of a molecule into FieldView, editing them to remove undesirable conformations, then pasting them back into FieldTemplater.

FieldTemplater’s new preferences section gives control over the look and feel of the application including, for the first time, the option to generate a stereo view in the 3D window. We’ve provided support for the four most common methods of generating stereo images but if we’ve missed one then just let us know.  Just like FieldView and FieldAlign, FieldTemplater enables the creation of high resolution images to enable communication of your results with colleagues or with the wider community.

This release also brings FieldTemplater onto the Mac, expanding our range of native Mac applications. We are now close to our goal of releasing Mac native versions of all of our desktop applications.

Picture of 4 p38 actives in a template

The best template found from 4 known p38 actives (pdb codes 3gcq, 3gpo, 3nmw, 3kji4). The template is remarkably similar to the alignment obtained with protein crystal structures and clearly shows that two compounds do not interact with the hinge region.

If you like what you’re hearing you can try the new version of FieldTemplater for free, just register here and we’ll send you a 1 month license together with download links.  Existing customers should contact their account manager for details.