A fields-based perspective on polypharmacology

Many biological events are a consequence of the interaction of a cascade of proteins, each one triggering the next. Organisms can often work around one, or even two, missing or damaged components; but we suspect they struggle to complete processes that are impaired at three or more points [01]. The historical way of dealing with…

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CloudScientific appointed as Cresset’s distributor in China

Cambridge, UK – 9th July 2014 – Cresset, innovative provider of computational chemistry software and services, announces the appointment of CloudScientific as distributor of their computational chemistry software in China. “The appointment of CloudScientific provides us with a dedicated channel to deliver our tools to the Chinese marketplace and will enable us to respond to…

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Forge V10.3: Significant new science, visualization and integration for leading ligand-based drug design workbench

Cambridge, UK – 3rd July 2014 – Cresset, innovative provider of computational chemistry software and services, announces the release of Forge V10.3. This major new release includes significant enhancements to the science, visualization, and integration of Forge, the computational workbench for ligand-based drug design, including significant enhancements to Activity Miner. “Activity Miner has been a…

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Outsourcing computational chemistry for drug discovery

The trend to outsource is making computational chemistry methods affordable and accessible for smaller research organisations. In IPI Volume 6 Issue 2 on pages 28 to 30 I outline the scientific and business reasons for outsourcing this important drug discovery method in IPI Volume 6 Issue 2 on pages 28 to 30. Outsourcing Computational Chemistry…

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Torch V10.3 delivers intuitive visualization and analysis tools for multiple parameter optimization

Cambridge, UK – 30th June 2014 – Cresset, innovative provider of computational chemistry software and services, announces the release of Torch V10.3. This version includes significant new science enabling medicinal chemists to visualize and optimize multiple activities to make the best molecular design decisions. “An important part of modern medicinal chemistry is to understand how…

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