June 2017 newsletter

Flare release imminent: New insights for structure-based design With the release of Flare imminent, Tim Cheeseright acknowledges the dedicated alpha and beta testers who have contributed to this exciting new application for structure-based design. Molecular design towards Protein-Protein Interaction inhibitors Martin Slater explores a powerful combination of cutting edge ligand and structure-based modeling using Flare

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Cresset applications licensed by Shiv Nadar University, India, to teach computational chemists of the future

Cambridge, UK – 20 June 2017 – Cresset, innovative provider of software and contract research services for small molecule discovery and design, announces that the Shiv Nadar University, India, has licensed the following applications to educate the computational chemist of the future: Forge – powerful ligand-focused workbench for SAR and design; and Spark – scaffold

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Molecular design towards Protein-Protein Interaction inhibitors

In December 2016 I attended the SCI Protein-Protein Interaction symposium. Armed with Cresset’s powerful ligand centric molecular modeling suite Forge, and an embryonic version of our new structure-based design application, Flare, I was keen to see what could usefully be done with PPI’s. Prof. Richard Baylis (University of Leeds, UK) presented new data on the

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Flare release imminent

New insights for structure-based design, thanks to our testers With the release of Flare imminent, I would like to thank all our dedicated alpha and beta testers for their time and patience. Your work has been invaluable to directing the final stages of development and smoothing out workflows before the full release. Throughout the development

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Re-Pharm and Cresset Discovery Services to attend BIO International for partnering

Cambridge, UK – June 13, 2017 – Cresset, innovative provider of software and contract research services for small molecule discovery and design, and Re-Pharm, an early-stage drug discovery and development company that uses computational chemistry for re-profiling, will attend BIO International in San Diego on June 19-22. “I am looking for partners to progress the

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May 2017 newsletter

Last chance to register for The Cresset User Group Meeting Register by 16th June to secure your place at our 15th Anniversary User Group Meeting. June 29th, Scientific program Official launch of Flare, our new structure-based design application Update on science and ligand-based design applications Customers share their experience of Cresset technology Limited accommodation available

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What can Torch do for you that TorchLite can’t?

Abstract TorchLite is the powerful freeware 3D molecule viewer, editor and design tool from Cresset. However, there are situations in which modeling with TorchLite is simply not enough and you need to access the full power of Torch. This blog post highlights some of the features which make Torch a powerful molecular design tool for medicinal

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Help with writing your grant application

Don’t wait until you have funding to talk to Cresset Discovery Services about working together. We can help before you even start writing your grant application. Our experience in helping write grant applications for academic and government funding shows that working together at the very start of a project reaps rewards. Being involved from the

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Water stability is key to designing novel patentable chemistry

An analysis of the water stability and positions in a ligand-protein complex informed the design of novel ligands for a customer target. This work led to new active chemistry that the customer went on to patent. A Cresset Discovery Services customer had identified a novel target with a natural ligand and were looking for new

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Scientific program and workshops announced for The Cresset User Group Meeting, 29th – 30th June 2017, Cambridge, UK

Cambridge, UK – 10 May 2017 – Cresset, innovative provider of software and contract research services for small molecule discovery and design, announces full line-up for The Cresset User Group Meeting, 29th – 30th June 2017 in Cambridge, UK. The scientific program on 29th June 2017 features speakers from 4 continents. Cresset scientists will present

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