An incredibly cost effective way of finding a chemical starting point

Many customers engage Cresset Discovery Services (CDS) to find a chemical starting point for their project. The input could be a competitor compound, a peptide, or a compound that is unsuitable for development for toxicity or patent reasons. Cresset computational methods are an extremely cost effective way of identifying promising candidate compounds. Identifying a patentable

Read More…

May 2016 newsletter

North American User Group Meeting Date: June 1st Venue: Novartis, Cambridge, MA Presenting companies: Boehringer Ingelheim, Broad Institute, Novartis, Cresset Last chance to register   European User Group Meeting Scientific program: June 16th Workshops: June 17th Venue: Granta Centre, Cambridgeshire, UK Presenting companies: Boehringer Ingelheim, Eli Lilly, GlaxoSmithKline, Monsanto, Novartis, Takeda, University of Hertfordshire, Cresset

Read More…

Using the Spark reagent databases to identify bioisosteric R-group replacements

Giovanna Tedesco Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract The reagent databases1 available with Cresset’s Spark2 software for bioisosteric replacement were used to identify alternative decorations for a series of triazolopyridazine and 8-fluorotriazolopyridine selective inhibitors of the c-Met Kinase. The use of databases derived from available reagents ensured that the... Read More…

Cresset announces scientific programs for User Group Meetings 2016

North American User Group Meeting: 1st June 2016, Cambridge, MA, USA European User Group Meeting: 16th – 17th June 2016, Cambridge, UK Cambridge, UK – 3rd May 2016 – Cresset, innovative provider of software for small molecule discovery and design, is pleased to announce their North American and European User Group Meetings, both taking place

Read More…

April 2016 newsletter

Spark V10.4 released A new version of Spark, our scaffold hopping and bioisostere replacement tool, is now available. V10.4 includes many new or improved features and gives access to new and updated chemical diversity. See the release announcement and view the video What’s new in Spark V10.4.   New Spark databases Spark V10.4 comes with

Read More…

April 2016 release of new Spark databases

The new release of Spark comes with new and updated fragment and reagent databases. These are designed to give you the widest sources of inspiration for your projects, whilst also enabling a close link between Spark’s suggestions and the chemistry that is available to you. Fragment Databases The latest Spark databases include over 3.5 Million

Read More…

Spark V10.4 released

A new version of Spark, our scaffold hopping and bioisostere replacement tool, is now released. V10.4 includes many new or improved features and gives access to new and updated chemical diversity. The development of our applications is guided by our customers and this release is bursting with new features and science that you have asked

Read More…

SAI Life Sciences Limited, India, licenses Cresset molecular design tools to advance customer projects

Cambridge, UK – 26th April 2016 – Cresset, an innovative provider of software and contract research services for small molecule discovery and design, is pleased to announce that SAI Life Sciences, a CDMO service provider with headquarters in Hyderabad India, has licensed several Cresset molecular design tools to advance their customer projects. “We are pleased

Read More…

Bridge resource gaps with Cresset Discovery Services

Cresset Discovery Services (CDS) interviewed, hired, trained and placed computational chemistry staff at a customer site. This involved the successful transition from a client outsourcing computational chemistry to having their own in-house resource. Cresset and the client continue to collaborate on ongoing projects. Outsourcing computational chemistry to CDS CDS has provided an outsourced computational chemistry

Read More…

Level Five appointed as Cresset’s distributor in Japan

株式会社レベルファイブ(本社:港区)と英Cressetは、日本におけるビジネスデベロップメントを共同で実施します Cambridge, UK – 5th April 2016 – Cresset, innovative provider of software and discovery services for small molecule discovery and design, announces the appointment of Level Five Co. Ltd. as distributor of their computational chemistry software and services in Japan. “The appointment of Level Five provides us with a dedicated channel to deliver our

Read More…