Spark is an exciting and powerful way of generating novel and diverse structures for your project. It is used by both synthetic/medicinal chemists and computational chemists. Spark uses Cresset’s field technology to find biologically equivalent replacements for key moieties in your molecule, enabling you to find new structures in new chemical space.
Use Spark computational chemistry software to optimize your leads and improve your IP position, or to switch scaffolds completely while retaining activity and minimizing ADME and toxicity issues.
Spark has an easy to use interface that quickly generates a range of lead molecules from an initial 2D structure and helps you choose the most innovative and tractable leads with the properties you need.