Update the way you see and draw molecules
Free 3D molecule viewing, editing and drawing
torchV10lite gives you a rich, informative view of how your molecules behave in biological systems. The powerful molecular viewer, editor and sketcher shows your molecules in 3D overlaid with field patterns together with 2D structure and physicochemical properties.
torchV10lite gives insight into how a compound’s activity, ADME and toxicity profiles relate to its molecular fields. You can filter molecules based on the exact mix of properties you need to progress your project. Full copy and paste support enables you to transfer molecules between applications and share your results with other team members. torchV10lite enables you to:
- Sketch your chemical series to study how field and activity patterns are related.
- Import and compare up to 10,000 compounds from SDF, MOL2 or Cresset applications.
- Convert from 2D to a minimized 3D conformation.
- Clone and compare molecules side by side or overlaid using Cresset’s unique field technology.
- View virtual screening results, comparing 2D structures with a 3D overlay showing the fields for every ligand.
Platforms: Windows, Linux, Mac, KNIME. Learn more.
torchV10lite is free software that you can download today.
Working with torchV10lite
The changing fields and properties associated with different members of a lead series. Molecules with the desired mix of physicochemical and experimental properties (such as IC50 data if available) can be selected using filters.
A deep visual understanding of complex SAR
torchV10lite enables you to load your structures from SDF and MOL2 files as well as showing results from all Cresset applications. You can import and compare up to 10,000 compounds at once or copy and paste them into torchV10lite from your favorite drawing package.
Do more than just view molecules with an upgrade to torchV10
torchV10lite is an excellent way to view and edit structures in 3D, helping you to understand how your molecules behave in a biological context. However, with an upgrade to torchV10 you can go further, gaining more knowledge, more quickly. See how they compare in the table below.
| Load protein-ligand crystal structures to visualize favorable interactions. | ||
| Load up to 10,000 molecules and convert them into 3D so 2D and 3D structures can be viewed side by side. | ||
| Load results of a ligand or protein based virtual screening experiment. | ||
| Study SAR of congeneric series by manually modifying structures and visualizing the change in the electrostatic and shape characteristics of the molecules. | ||
| Align and compare molecules using a common substructure or using electrostatic and shape characteristics. | ||
| Gain immediate feedback on new designs using the ‘score while you draw’ feature. | ||
| Automatically create energetically reasonable conformations for new designs and ensure these can bind to your target. | ||
| Score new molecules against detailed 3D QSAR models from Cresset’s forgeV10 software. | ||
| Optimize more than potency with the optional StarDrop module to predict off-target effects. |
Interested? Take a free evaluation of torchV10 and start designing your next molecule using the power of fields.
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