Discovery
Why Cresset Discovery?
As your computational chemistry CRO, our experts bring a unique perspective to help you remove obstacles, and save time and money, to advance your drug discovery project performance
Collaboration sparks new methods and ideas
- Whatever your project, we share your goals and challenges
- It's our business to help you achieve project milestones
- Projects can be staged with key milestones and deliverables planned in advance
- We will never try to sell you a task that will not help
Experts with extensive industry experience
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The range of starting points, project types and development requirements we have experience with is extensive, so the chances are we already have experience relevant to advance your project
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As our scientists have complementary skills, knowledge and experience, we can match the right consultant, with the correct expertise, to your project to deliver maximum value
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We have completed hundreds of contract research projects with many of the global top pharmaceutical, biotech, agrochemical and flavor and fragrance companies
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Our experts have an excellent track record in discovery research
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We propose methods that provide answers in the most intelligent and innovative way
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We're excited by new challenges and by the synergistic nature of contract research
Flexible, demand driven resources to optimize the value of your research investment
- We will help you create a service package that suits your needs, whether that be a matter of days or a long-term collaboration over years
- Projects can be staged with key milestones and deliverables planned in advance
- Pay for only the services you need to reach your goals
- Access our expertise where and when you need it to eliminate unnecessary overheads while obtaining a world class service
- Obtain exactly the resources and support you need for the projects at hand
What you need to start your project with us
- A challenging project in the field of drug discovery, biotechnology, agrochemicals, flavors, fragrances: this could be as generic as how to develop an idea, to a very focuses issue with a lead compound, or anything in-between
- No-risk free confidential discussion with our CADD experts: this often rapidly leads to the identification of potential avenues to develop your project, which can be expanded into a project proposal upon request
Testimonials from Cresset Discovery customers
Working closely with the Cresset Discovery team we aimed to identify a putative binding pose for a lead series in published PDB coordinates that was not only consistent with the kinetically deduced MOA but explained the established SAR as well. The furnished results were able to satisfy these goals and then be applied prophetically for ligand design purposes.
Twentyeight-Seven Therapeutics, USA
We sought the scientific expertise within the Cresset Discovery team to utilize their novel field and shape-based virtual screening methods in Blaze™, and their proprietary Electrostatic Complementarity™ technique to help identify a backup series for our target effectively and efficiently. Ultimately we identified 9 novel chemotypes that were clearly distinct to those arising from docking and pharmacophore virtual screening approaches, which was an exciting outcome for us.
Dr Zara Sands, Head of CADD and Informatics, Confo Therapeutics, Belgium
Through the work presented to us I was particularly impressed with the data management and visualization within Forge, so the next step was for us to use it in-house. We will use Forge alongside our continuing consulting work with Cresset to aid in the development of our understanding of the SAR and design of future antifungal agents.
Dr Graham Sibley, Head of Chemistry, F2G, UK
We really like the powerful combination of excellent software tools and molecular design expertise which we get from working with Cresset.
Dr Graham Sibley, Head of Chemistry, F2G, UK
Cresset is a valuable partner in our drug discovery programs. Their deep knowledge of computational chemistry and its application to drug discovery is enabling us to progress multiple projects across a wide range of target classes very quickly and cost-effectively. Cresset has consistently delivered insightful support to our drug discovery efforts. In our experience, their knowledge, responsiveness and collaborative approach have set them apart from their competitors.
CEO, Pharmaceutical company, UK
Cresset Discovery’s computational experience and high standard of scientific support is ideally suited to help drive the next stage of this project.
Dr Richard Boyce, Senior Director of Research at PhoreMost