TORX® DMTA
Case studies and application notes
See real-world examples of how Torx supports organizations operating in drug discovery, by driving productivity through improved collaboration and information exchange
- Monte Rosa Therapeutics: Coordinating synthetic chemistry efforts with CROs and registering directly into CDD Vault
- Engine Biosciences: Transforming the way design and synthesis knowledge is captured and shared internally and with CROs
- Clinical-stage biopharma: Synthetic target tracking simplifying management of multiple CROs
- Boston-based biotech: Creation of knowledge base reducing chances of duplicating effort and becoming an integral part of informatics ecosystem
- Application note: Using Torx® Make for CRO projects
- Cloud-based solutions: enhancing AI-human interaction for faster drug discovery
Torx DMTA testimonials
The ability to see progress across projects for design and synthesis helps us work out where there are hold-ups so we can make informed resourcing decisions
Top 10 global pharmaceutical company
Torx has revolutionised the way we communicate & prioritise designs within project teams and with our synthetic chemistry CRO partners. Working across multiple projects and with a range of external partners, we have embedded the software into our workflows to improve chemistry delivery. Torx has enabled increased flexibility in working with our collaborators and improved communication of relative priorities. We can make informed decisions quickly and track delivery of key molecules to rapidly advance our programs.
Associate Director, Medicinal Chemistry, Cambridge Biotech
Torx Make has immediately become integral to Monte Rosa’s informatics ecosystem and is fundamental to the way that chemists work. The integration with in-house databases has provided additional efficiencies for our CRO partners and Monte Rosa chemists, removing manual registration steps. Torx Make readily scales with our expanding requirement to leverage more externalized chemistry.
Bernhard Fasching, Vice President, Chemistry at Monte Rosa
Torx Make has rapidly become a crucial node in Evariste's chemistry platform and is essential to the way we communicate with CROs. Our virtual model means that efficient interaction with our external chemists is fundamentally important and Torx Make has helped significantly in this regard. We look forward to further expanding our use of the Torx platform as Evariste grows.
Alfie Brennan, Chief Scientific Officer, Evariste
It is easy to identify any productivity bottlenecks, make quick and informed decisions about changes to priorities or assignments, and communicate these updates to team members and CROs. By providing immediate, real-time access to design and synthesis information, Torx ensures that we are investing our resources in the most critical compounds.
Toni Kline, Senior Director of Chemistry at Engine Biosciences
We were relying on emails to exchange information, which ended up either in PDFs buried in a file share or in people’s memory. It was difficult to keep track of who was making what, or to find out if something had been done before, which meant that people at different locations were working on the same target and some compounds were re-proposed unnecessarily. There was also the risk of timelines sliding because an important compound went under the radar and wasn’t worked on in a timely manner.
Director of Informatics, Boston-based biotech
"During my time at AstraZeneca I was working with what was chemTraX and I really liked it- I appreciated the usefulness, how easy it is to work with. When I joined Evariste they were already using Torx…so when I learned I’d be using Torx Make I was really pleased!”
Jan Lanz, Principal Chemistry Scientist, Evariste