July 2019 newsletter
The importance of understanding protein-protein and protein-ligand interactions in immuno-oncology Immuno-oncology represents a new paradigm in the fight against cancer and ...
Version 3.1 of our popular XedTools package, giving access to our unique molecular mechanics force field, is now available. A new addition in this release is the incoporation of visualization plugins that enable the viewing of Cresset’s field points in third party applications. Read more.
Molecule alignment is a central task to all experiments in Torch and Forge. In this web clip we show how to quickly and easily align diverse molecules using the wizard in Torch althought he steps are the same in Forge. See web clip.
Cresset’s technology compares molecules using shape and electrostatic similarity simultaneously. In this short web clip we introduce the field point technology that enables these comparisons. See web clip.
Dr. Andy Vinter explains a fields-based perspective on polypharmacology including using polypharmacophores to combine protein templates, incorporating negative field patterns for selectivity and building structurally diverse polypharmacological libraries. Read article.