August 2019 newsletter
Sneak peek at Flare V3.0 for structure-based design Giovanna Tedesco gives a sneak peek at some of the new functionality in Flare ...
Dr. Andy Vinter asks a big question – ‘Can the XED molecular mechanics force field be applied to proteins?’ Read the article.
Is it possible to find an inhibitor that will be able to conform to the requirements of the protein’s location, shape and lipophilicity? Dr. Martin Slater discusses the complex factors which determine whether a protein is druggable. Read the article.
The new reagent databases enable rapid assessment of your available chemistry. In this case study we use them to revisit a fragment growing experiment. Read the article.