June 2019 newsletter
Therapeutic protein degradation by design; Presentations from recent meetings; Review of Efficient Drug Discovery Through Connected Chemistry symposium; New website
Dr. Andy Vinter asks a big question – ‘Can the XED molecular mechanics force field be applied to proteins?’ Read the article.
Is it possible to find an inhibitor that will be able to conform to the requirements of the protein’s location, shape and lipophilicity? Dr. Martin Slater discusses the complex factors which determine whether a protein is druggable. Read the article.
The new reagent databases enable rapid assessment of your available chemistry. In this case study we use them to revisit a fragment growing experiment. Read the article.