Capturing accessible chemistry space

There is often a divide between computational results and synthetic accessibility in the identification process of alternative compounds. However, there is now a way to produce results more quickly and precisely, and to ultimately accelerate the research process.

Our article Chemical Reaction discusses:

• Scaffold hopping
• Case studies:
  • Finding bioisosteres of DPP-IV inhibitors
  • Identifying optimization routes
• Fragment reconnection
• Accessible chemistry
• Available synthetic chemistry

This article is taken from Innovations in Pharmaceutical Technology July 2016, pages 16-19. © Samedan Ltd