November 2023 Newsletter
This month's latest news: cost-effective and easy-to-run FEP calculations with Flare™ FEP, Q&A with a San Francisco-based biotech on their ...
Optimize your decision-making across the entire design-make-test-analyze (DMTA) cycle with this month's collection of CADD software features, expert scientific opinion, and first-class drug discovery research resources.
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In our recent thought leadership webinar with FierceBiotech, we explored the transformational role that technology can play within the changing working landscape of drug discovery. The webinar was chaired by our CEO, Rob Scoffin, who welcomed a panel of expert guest speakers, from a variety of drug discovery organizations for an insightful discussion. Catch up, via the session recording, and hear what they had to say
In this case study, we demonstrate how careful systems preparation using Molecular Dynamics (MD) and water analysis, prior to FEP calculations can improve results and reduce the number of calculations required to obtain reliable and accurate predicted binding affinities.
Activity prediction in drug discovery is typically reliant on the availability of a protein structure, and structure-based methods such as docking. In this case study, we reinforce the value of ligand-based methods, by demonstrating how 3D QSAR methods in Flare™ were used to generate predictive models of Phosphodiesterase 10A (PDE10A) activity.
The requirement to develop novel classes of antibiotics has never been greater. We discuss the challenges in navigating antibacterial drug design, and how intelligent computational technologies and approaches can be used to harvest valuable insights to accelerate discovery.
We recently held the official opening of the Vinter Suite at our head office in Cambridgeshire, UK. Named after our founder, Andy Vinter, the Vinter Suite comprises flexible meeting and networking spaces.
Cresset are due to be attending, exhibiting, and/or presenting at the following events. Further details can be found via our upcoming events schedule.
CBI Annual Meeting 2023
23 - 26 October | Tokyo, Japan
25 - 28 October | Durham, USA
4th World Congress on Drug Discovery & Development 2023
29 October | Bengaluru, India
Medicinal Chemistry Strategy Meeting East Coast USA 2023
08 November | Boston, USA
Chemist in Industry
15 November | London, UK
EFMC-ISCB International Symposium on Chemical Biology
16 - 18 November | London, UK